ISSN 1662-4009 (online)

ey0015.10-2 | Aetiology and heterogeneity of type 1 diabetes | ESPEYB15

10.2 Higher parental occupational social contact is associated with a reduced risk of incident pediatric T1DM: mediation through molecular enteroviral indices

AL Ponsonby , A Pezic , FJ Cameron , C Rodda , AS Kemp , JB Carlin , H Hyoty , A Sioofy-Khojine , T Dwyer , JA Ellis , ME Craig

To read the full abstract: PLoS One. 2018;13:e0193992Enterovirus infections in children are associated with an almost 10-fold higher risk of T1DM. In these families in parents and siblings enterovirus can frequently be detected by PCR. However, the role of enteroviral infections in the pathogenesis of T1DM is complex. Although enterovirus infections are less prevalent T1DM incidence increa...

ey0019.14-10 | Risk and Outcome | ESPEYB19

14.10. Childhood cardiovascular risk factors and adult cardiovascular events

DR Jr Jacobs , JG Woo , AR Sinaiko , SR Daniels , J Ikonen , M Juonala , N Kartiosuo , T Lehtimaki , CG Magnussen , JSA Viikari , N Zhang , LA Bazzano , TL Burns , RJ Prineas , J Steinberger , EM Urbina , AJ Venn , OT Raitakari , T Dwyer

N Engl J Med. 2022 May 19;386(20):1877–1888. doi: 10.1056/NEJMoa2109191.Brief summary: This prospective cohort study leveraged data from the International Childhood Cardiovascular Cohorts (i3C) Consortium, including 42 324 participants at baseline and followed-up over a mean of 35 years, in order to investigate associations between cardiovascular risk factors (CVRF, including body-mass ind...